After repeated verification of this fact,he decided to stop the practice of Orthodox system of medicine.Once he wrote to his friend" I have been putting drugs of which I know little into bodies of which I know less; so I can but renounce the practice of medicine that I no longer incur the risk of doing injury"
He was a genius having the knowledge of 14 languages and an authority in subjects like Chemistry, Philosophy, Pharmacy etc. So he engaged in translating books from different languages to German for his livelihood. While translating Cullen's Materia Medica from English to German language, he came upon the remarks of Cullen about the ague- curing property of Cinchona-bark and his explanation of the modus operendi of that drug i.e., by virtue of bitterness, the drug cured the malaria. This explanation did not satisfy Hahnemann. There were plenty of bitter drugs known to him but they did not have the ability to cure malaria. So he decided to test the action of Cinchona-bark on his own body. After talking a few doses of the decotion (tincture) made out of the bark he developed symptoms similar to malarial fever. He realized the power of producing malaria like symptoms in healthy bodies. After this he proved and reproved several other drugs and confirmed the fact that a drug that can cure a disease has the property of producing similar symptoms in a healthy man. He explained this natures law of cure as "Let likes be treated by likes " or " Similia Similibus Curentur". Thus Homoeopathy was born when Hahnemann published an article in Hufeland's journal under the title " An Essay on a New principle for Ascertaining the Curative powers Drugs ". He then conducted years of experiments and study and the complete systemization of the principles and practice of Homoeopathic art of healing was effected with the publication of Hahnemann's Organon of medicine in 1810.

In this Science, the diseased state is assessed in terms of externally expressed symptoms and analysed in relation to the constitutional, mental, emotional and hereditary aspects. This method helps to pinpoint the root cause of the disease and to treat for a radical cure.

The Homoeopathic Medicines are also designed to exclude all the side effects and reactions by minimizing the drugs strength and activating the inherent medicinal properties by potentising the same.

This system differs in many ways from the conventional methods of treatment. The peculiar way of study of disease states, manufacturing and application of medicine are not seen in any other system.

Homoeopathic medicines are prepared by a unique method termed potentisation.

It is done in two steps:
(1) diluting the crud drug with the vehicle (usally Ethyl Alcohol) in a definite proportion and
(2) activation of medicinal properties by succussion or impact mixing.

The medicines prepared in this method in required potency is used in single doses to stimulate the immune system or the vital force to act against the diseased state. Thus Homoeopathic treatment always bringing radical cure i.e., here the vital force itself is engaged in the correction of diseased state, on stimulation received from the Homoeopathic medicine, where as in other systems, medicines are directly engaged in treatment of aliments. There for the cure will always be incomplete or if cured that may cause some side effects.