| 1974 | Society Registered at Thiruvanthapuram as The Kerala State Homoeopathic Co-operative Pharmacy Ltd. No. T 432 |
| 1975 | Society came in to functioning |
| 1977 | First factory building foundation stone laid at Alappuzha |
| 1978 | Factory building commissioned |
| 1980 | HOMCO products are launched to open market |
| 1989 | Second factory building inaugurated |
| 2001 | Separate Quality Control and R&D Division started |
| 2003 | New Unit for Globule and External preparations started |
| 2006 | Drug Dynamization Block commissioned |
| 2007 | Medicinal plant farm started |
| 2008 | HOMCO’s second expansion programme commenced. Medicine Export started |
| 2009 | ISO 9001 – 2000 Certification |
| 2018 | New Factory Building Construction Started |
| 2021 | New Factory Building Inauguration |